Preheat oven to 425°F (220°C). Line a baking sheet with parchment paper.
Cut cauliflower into florets and pulse in a food processor until it resembles rice.
Microwave cauliflower rice for 4-5 minutes until tender. Let cool slightly, then place in a clean towel and squeeze out as much moisture as possible.
Transfer cauliflower to a bowl. Stir in eggs, mozzarella, parmesan, oregano, garlic powder, and salt until well combined.
Shape mixture into a round crust about 1/4 inch thick on the prepared baking sheet.
Bake for 20 minutes or until golden brown and firm.
Remove from oven, add desired toppings, and bake an additional 5-10 minutes until toppings are cooked.